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1

Arrhythmogenic right ventricular cardiomyopathy in Boxer dogs is associated with calstabin2 deficiency

Mark A. Oyama, Steve Reiken, Stephan E. Lehnart, Sridar V. Chittur, Kathryn M. Meurs, Joshua Stern, Andrew R. Marks

Journal:

Journal of Veterinary Cardiology

Year:

2008

Language:

english

File:

PDF, 1.23 MB

english, 2008

2

Modulation of the Ryanodine Receptor and Intracellular Calcium

Zalk, Ran, Lehnart, Stephan E., Marks, Andrew R.

Journal:

Annual Review of Biochemistry

Year:

2007

Language:

english

File:

PDF, 475 KB

english, 2007

3

In vivo model with targeted cAMP biosensor reveals changes in receptor–microdomain communication in cardiac disease

Sprenger, Julia U., Perera, Ruwan K., Steinbrecher, Julia H., Lehnart, Stephan E., Maier, Lars S., Hasenfuss, Gerd, Nikolaev, Viacheslav O.

Journal:

Nature Communications

Year:

2015

Language:

english

File:

PDF, 1.31 MB

english, 2015

4

K201 improves aspects of the contractile performance of human failing myocardium via reduction in Ca2+leak from the sarcoplasmic reticulum

Karl Toischer, Stephan E. Lehnart, Gero Tenderich, Hendrik Milting, Reiner Körfer, Jan D. Schmitto, Friedrich A. Schöndube, Noboru Kaneko, Christopher M. Loughrey, Godfrey L. Smith, Gerd Hasenfuss, Ti

Journal:

Basic Research in Cardiology

Year:

2010

Language:

english

File:

PDF, 471 KB

english, 2010

5

Abnormalities of calcium metabolism and myocardial contractility depression in the failing heart

Stephan E. Lehnart, Lars S. Maier, Gerd Hasenfuss

Journal:

Heart Failure Reviews

Year:

2009

Language:

english

File:

PDF, 325 KB

english, 2009

6

Sarcoplasmic Reticulum Proteins in Heart Failure

STEPHAN E. LEHNART, WOLFGANG SCHILLINGER, BURKERT PIESKE, JÜRGEN PRESTLE, HANJÖRG JUST, GERD HASENFUSS

Journal:

Annals of the New York Academy of Sciences

Year:

1998

File:

PDF, 872 KB

1998

7

Cardiac Ryanodine Receptor Function and Regulation in Heart Disease

STEPHAN E. LEHNART, XANDER H. T. WEHRENS, ALEXANDER KUSHNIR, ANDREW R. MARKS

Journal:

Annals of the New York Academy of Sciences

Year:

2004

File:

PDF, 6.88 MB

2004

8

Ryanodine Receptor-Targeted Anti-Arrhythmic Therapy

XANDER H.T. WEHRENS, STEPHAN E. LEHNART, ANDREW R. MARKS

Journal:

Annals of the New York Academy of Sciences

Year:

2005

Language:

english

File:

PDF, 341 KB

english, 2005

9

Frequency-dependence of Myocardial Energetics in Failing Human Myocardium as Quantified by a New Method for the Measurement of Oxygen Consumption in Muscle Strip Preparations

Markus Meyer, Boris Keweloh, Konrad Güth, Jeffrey W. Holmes, Burkert Pieske, Stephan E. Lehnart, Hanjörg Just, Gerd Hasenfuss

Journal:

Journal of Molecular and Cellular Cardiology

Year:

1998

Language:

english

File:

PDF, 392 KB

english, 1998

10

Preservation of Contractile Characteristics of Human Myocardium in Multi-day Cell Culture

Paul M.L. Janssen, Stephan E. Lehnart, Jürgen Prestle, Gerd Hasenfuss

Journal:

Journal of Molecular and Cellular Cardiology

Year:

1999

Language:

english

File:

PDF, 223 KB

english, 1999

11

Calstabin deficiency, ryanodine receptors, and sudden cardiac death

Stephan E. Lehnart, Xander H.T. Wehrens, Andrew R. Marks

Journal:

Biochemical and Biophysical Research Communications

Year:

2004

Language:

english

File:

PDF, 3.44 MB

english, 2004

12

Phosphodiesterase 4D Deficiency in the Ryanodine-Receptor Complex Promotes Heart Failure and Arrhythmias

Stephan E. Lehnart, Xander H.T. Wehrens, Steven Reiken, Sunita Warrier, Andriy E. Belevych, Robert D. Harvey, Wito Richter, S.-L. Catherine Jin, Marco Conti, Andrew R. Marks

Journal:

Year:

2005

Language:

english

File:

PDF, 568 KB

english, 2005

13

Phosphodiesterase 4D Deficiency in the Ryanodine-Receptor Complex Promotes Heart Failure and Arrhythmias

Stephan E. Lehnart, Xander H.T. Wehrens, Steven Reiken, Sunita Warrier, Andriy E. Belevych, Robert D. Harvey, Wito Richter, S.-L. Catherine Jin, Marco Conti, Andrew R. Marks

Journal:

Year:

2005

Language:

english

File:

PDF, 95 KB

english, 2005

14

Novel targets for treating heart and muscle disease – stabilizing ryanodine receptors and preventing intracellular calcium leak

Stephan E Lehnart

Journal:

Current Opinion in Pharmacology

Year:

2007

Language:

english

File:

PDF, 531 KB

english, 2007

15

An antidote for calcium leak: Targeting molecular arrhythmia mechanisms

Stephan E. Lehnart, W.J. Lederer

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2010

Language:

english

File:

PDF, 298 KB

english, 2010

16

FKBP12.6 Deficiency and Defective Calcium Release Channel (Ryanodine Receptor) Function Linked to Exercise-Induced Sudden Cardiac Death

Xander H.T. Wehrens, Stephan E. Lehnart, Fannie Huang, John A. Vest, Steven R. Reiken, Peter J. Mohler, Jie Sun, Silvia Guatimosim, Long-Sheng Song, Nora Rosemblit, Jeanine M. D'Armiento, Carlo Napoli

Journal:

Year:

2003

Language:

english

File:

PDF, 729 KB

english, 2003

17

Sted Based Super-Resolution Imaging of Transverse Tubules in Ventricular Myocytes

Wagner, Eva, Lauterbach, Marcel, Westphal, Volker, Hagen, Brian, Lederer, W.J., Hell, Stefan W., Lehnart, Stephan E.

Journal:

Biophysical Journal

Year:

2010

Language:

english

File:

PDF, 41 KB

english, 2010

18

Stochastic Simulation Assessing the Functional Changes Occurring during Heart Failure

Tuan Hoang-Trong, Minh, Williams, George S.B., Lehnart, Stephan E., Lederer, W. Jonathan, Jafri, Mohsin S.

Journal:

Biophysical Journal

Year:

2012

Language:

english

File:

PDF, 40 KB

english, 2012

19

Ryanodine receptors as drug targets for heart failure and cardiac arrhythmias

Stephan E. Lehnart, Xander H.T. Wehrens, Andrew R. Marks

Journal:

Drug Discovery Today: Therapeutic Strategies

Year:

2005

Language:

english

File:

PDF, 451 KB

english, 2005

20

Superresolution microscopy in heart — Cardiac nanoscopy

Kohl, Tobias, Westphal, Volker, Hell, Stefan W., Lehnart, Stephan E.

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2013

Language:

english

File:

PDF, 820 KB

english, 2013

21

INTRACELLULAR CALCIUM RELEASE AND CARDIAC DISEASE

Wehrens, Xander H.T., Lehnart, Stephan E., Marks, Andrew R.

Journal:

Annual Review of Physiology

Year:

2005

Language:

english

File:

PDF, 427 KB

english, 2005

22

Voltage Sensitive Protein 2.3: A Novel Tool to Study Sarcolemmal Structure and Electrical Activity in Mouse Hearts

Liao, Mei-Ling Chang, Mutoh, Hiroki, Iwamoto, Yuka, Raad, Nour, Nikolaev, Viacheslav, Luther, Stefan, Lehnart, Stephan, Wagner, Stefan, Maier, Lars, Stühmer, Walter, Knöpfel, Thomas, Zimmermann, Wolfr

Journal:

Biophysical Journal

Year:

2011

Language:

english

File:

PDF, 51 KB

english, 2011

23

Mutant Ryanodine Receptor-dependent Calcium Leak, RyR2 Open Probability, Calcium Sparks And Cardiac Arrhythmogenesis

Lehnart, Stephan E., Ward, Chris W., Sobie, Eric A., Lederer, W.J.

Journal:

Biophysical Journal

Year:

2009

Language:

english

File:

PDF, 41 KB

english, 2009

24

Solute Transport in the Transverse Tubules of Cardiac Ventricular Myocytes

Hagen, Brian M., Lauterbach, Marcel A., Wagner, Eva, Hell, Stefan W., Lehnart, Stephan E., Lederer, W. Jonathan

Journal:

Biophysical Journal

Year:

2010

Language:

english

File:

PDF, 37 KB

english, 2010

25

Analysis of Fluorescence Microscopy Super-Resolution Data of Protein Assemblies

Kohl, Tobias, Parlitz, Ulrich, Hell, Stefan W., Luther, Stefan, Lehnart, Stephan E.

Journal:

Biophysical Journal

Year:

2013

Language:

english

File:

PDF, 38 KB

english, 2013

26

STED Nanoscopy of Cardiac RyR2 Clusters and Sub-Structure Analysis After Myocardial Infarction

Kohl, Tobias, Parlitz, Ulrich, Lauterbach, Marcel, Minh Tuan, Hoang-Trong, Williams, George S.B., Westphal, Volker, Jafri, M. Saleet, Lederer, W.J., Luther, Stefan, Hell, Stefan W., Lehnart, Stephan E

Journal:

Biophysical Journal

Year:

2012

Language:

english

File:

PDF, 40 KB

english, 2012

27

Super-Resolution Modeling of Calcium Release in Heart

Walker, Mark A., Williams, George S.B., Kohl, Tobias, Jafri, Saleet, Lehnart, Stephan E., Greenstein, Joseph L., Lederer, W.J., Winslow, Raimond L.

Journal:

Biophysical Journal

Year:

2014

Language:

english

File:

PDF, 43 KB

english, 2014

28

Principles of Network Organization of T-Tubule Membranes in Health and Disease

Kohl, Tobias, Wagner, Eva, Brandenburg, Soeren, Parlitz, Ulrich, Lederer, W.J., Lehnart, Stephan E.

Journal:

Biophysical Journal

Year:

2013

Language:

english

File:

PDF, 43 KB

english, 2013

29

Phosphodiesterase 4D and heart failure: a cautionary tale

Lehnart, Stephan E, Marks, Andrew R

Journal:

Expert Opinion on Therapeutic Targets

Year:

2006

Language:

english

File:

PDF, 236 KB

english, 2006

30

Understanding the physiology of heart failure through cellular and in vivo models-towards targeting of complex mechanisms

Lehnart, Stephan E.

Journal:

Experimental Physiology

Year:

2013

Language:

english

File:

PDF, 255 KB

english, 2013

31

Physiologic force-frequency response in engineered heart muscle by electromechanical stimulation

Godier-Furnémont, Amandine F.G., Tiburcy, Malte, Wagner, Eva, Dewenter, Matthias, Lämmle, Simon, El-Armouche, Ali, Lehnart, Stephan E., Vunjak-Novakovic, Gordana, Zimmermann, Wolfram-Hubertus

Journal:

Year:

2015

Language:

english

File:

PDF, 1.79 MB

english, 2015

32

Toward panoramic in situ mapping of action potential propagation in transgenic hearts to investigate initiation and therapeutic control of arrhythmias

Dura, Miroslav, SchrÃ¶der-Schetelig, Johannes, Luther, Stefan, Lehnart, Stephan E.

Journal:

Frontiers in Physiology

Year:

2014

Language:

english

File:

PDF, 1.12 MB

english, 2014

33

Optogenetic determination of the myocardial requirements for extrasystoles by cell type-specific targeting of ChannelRhodopsin-2

Zaglia, Tania, Pianca, Nicola, Borile, Giulia, Da Broi, Francesca, Richter, Claudia, Campione, Marina, Lehnart, Stephan E., Luther, Stefan, Corrado, Domenico, Miquerol, Lucile, Mongillo, Marco

Journal:

Proceedings of the National Academy of Sciences

Year:

2015

Language:

english

File:

PDF, 1.84 MB

english, 2015

34

Calcium/calmodulin-dependent protein kinase II (CaMKII) inhibition ameliorates arrhythmias elicited by junctin ablation under stress conditions

Tzimas, Christos, Terrovitis, John, Lehnart, Stephan E., Kranias, Evangelia G., Sanoudou, Despina

Journal:

Year:

2015

Language:

english

File:

PDF, 2.13 MB

english, 2015

35

Superresolution Modeling of Calcium Release in the Heart

Walker, Mark A., Williams, George S.B., Kohl, Tobias, Lehnart, Stephan E., Jafri, M. Saleet, Greenstein, Joseph L., Lederer, W.J., Winslow, Raimond L.

Journal:

Biophysical Journal

Year:

2014

Language:

english

File:

PDF, 819 KB

english, 2014

36

Intensity matters: Ryanodine receptor regulation during exercise

Kohl, Tobias, Weninger, Gunnar, Zalk, Ran, Eaton, Philip, Lehnart, Stephan E.

Journal:

Proceedings of the National Academy of Sciences

Year:

2015

Language:

english

File:

PDF, 783 KB

english, 2015

37

The molecular and functional identities of atrial cardiomyocytes in health and disease

Brandenburg, Sören, Arakel, Eric C., Schwappach, Blanche, Lehnart, Stephan E.

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Year:

2015

Language:

english

File:

PDF, 2.28 MB

english, 2015

38

PKA Phosphorylation Activates the Calcium Release Channel (Ryanodine Receptor) in Skeletal Muscle: Defective Regulation in Heart Failure

Steven Reiken, Alain Lacampagne, Hua Zhou, Aftab Kherani, Stephan E. Lehnart, Chris Ward, Fannie Huang, Marta Gaburjakova, Jana Gaburjakova, Nora Rosemblit, Michelle S. Warren, Kun-lun He, Geng-hua Yi

Journal:

The Journal of Cell Biology

Year:

2003

Language:

english

File:

PDF, 1.11 MB

english, 2003

39

Exercise training prevents ventricular tachycardia in CPVT1 due to reduced CaMKII-dependent arrhythmogenic Ca 2+ release

Manotheepan, Ravinea, Danielsen, Tore K., Sadredini, Mani, Anderson, Mark E., Carlson, Cathrine R., Lehnart, Stephan E., Sjaastad, Ivar, Stokke, Mathis K.

Journal:

Cardiovascular Research

Year:

2016

Language:

english

File:

PDF, 845 KB

english, 2016

40

Axial Membrane Tubules in Atrial Cardiomyocytes Confine Ultrarapid Intracellular Calcium Signals through a New Super-Hub Mechanism

Brandenburg, Sören, Kohl, Tobias, Williams, George S.B., Gusev, Konstantin, Wagner, Eva, Hebisch, Elke, Ward, Christopher W., Lederer, W.J., Lehnart, Stephan E.

Journal:

Biophysical Journal

Year:

2016

Language:

english

File:

PDF, 52 KB

english, 2016

41

“Reduced” Coumarin Dyes with an O -Phosphorylated 2,2-Dimethyl-4-(hydroxymethyl)-1,2,3,4-tetrahydroquinoline Fragment: Synthesis, Spectra, and STED Microscopy

Nizamov, Shamil, Sednev, Maksim V., Bossi, Mariano L., Hebisch, Elke, Frauendorf, Holm, Lehnart, Stephan E., Belov, Vladimir N., Hell, Stefan W.

Journal:

Chemistry - A European Journal

Year:

2016

Language:

english

File:

PDF, 3.27 MB

english, 2016

42

From Ribosome to Sarcomere - Titin Dynamics in Striated Muscle Cells

Gotthardt, Michael, Rudolph, Franziska, Huettemeister, Judith, da Sliva Lopes, Katharina, Yu, Lily, Bergmann, Nora, Fink, Claudia, Wagner, Eva, Lehnart, Stephan, Gregorio, Carol

Journal:

Biophysical Journal

Year:

2017

Language:

english

File:

PDF, 43 KB

english, 2017

43

How Does Calcium Overload Generate Calcium Waves in Heart?

Williams, George S.B., Wescott, Andrew P., Lehnart, Stephan E., Lederer, W.J.

Journal:

Biophysical Journal

Year:

2017

Language:

english

File:

PDF, 50 KB

english, 2017

44

Negative Adrenergic Feedback Specific to Phospholamban ∗

Hasenfuss, Gerd, Lehnart, Stephan E.

Journal:

JACC: Basic to Translational Science

Year:

2017

Language:

english

File:

PDF, 256 KB

english, 2017

45

Analysis of Tubular Membrane Networks in Cardiac Myocytes from Atria and Ventricles

Wagner, Eva, Brandenburg, Sören, Kohl, Tobias, Lehnart, Stephan E.

Journal:

Journal of Visualized Experiments

Year:

2014

Language:

english

File:

PDF, 4.24 MB

english, 2014

46

High-Affinity Functional Fluorescent Ligands for Human β-Adrenoceptors

Mitronova, Gyuzel Y., Lukinavičius, Gražvydas, Butkevich, Alexey N., Kohl, Tobias, Belov, Vladimir N., Lehnart, Stephan E., Hell, Stefan W.

Journal:

Scientific Reports

Year:

2017

Language:

english

File:

PDF, 6.23 MB

english, 2017

47

On the Adjacency Matrix of RyR2 Cluster Structures

Walker, Mark A., Kohl, Tobias, Lehnart, Stephan E., Greenstein, Joseph L., Lederer, W. J., Winslow, Raimond L., Saucerman, Jeffrey J.

Journal:

PLoS Computational Biology

Year:

2015

Language:

english

File:

PDF, 969 KB

english, 2015

48

Differential multivariable risk prediction of appropriate shock versus competing mortality - A prospective cohort study to estimate benefits from ICD therapy

Bergau, Leonard, Willems, Rik, Sprenkeler, David J., Fischer, Thomas H., Flevari, Panayota, Hasenfuß, Gerd, Katsaras, Dimitrios, Kirova, Aleksandra, Lehnart, Stephan E., Lüthje, Lars, Röver, Christian

Journal:

International Journal of Cardiology

Year:

2018

Language:

english

File:

PDF, 2.20 MB

english, 2018

49

Ca2+ signaling in the myocardium by (redox) regulation of PKA/CaMKII

Johnston, Alex S., Lehnart, Stephan E., Burgoyne, Joseph R.

Journal:

Frontiers in Pharmacology

Year:

2015

Language:

english

File:

PDF, 1.99 MB

english, 2015

50

Ryanodine receptor dysfunction and the resolution revolution: how Nobel Prize-winning techniques transform cardiovascular research

Voigt, Niels, Lehnart, Stephan E

Journal:

Cardiovascular Research

Year:

2018

Language:

english

File:

PDF, 363 KB

english, 2018

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